Interleukin-6 from mouse; IL-6; recombinant; expressed in E. coli; lyophilized powder; suitable for cell culture; carrier free

Code: I9646-25UG D2-231

Analysis Note

The biological activity of recombinant mouse IL-6 was measured in a cell proliferation assay using T1165.85.2.1 cells.

Biochem/physiol Actions

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€1,050.00 25UG
€1,291.50 inc. VAT

Analysis Note

The biological activity of recombinant mouse IL-6 was measured in a cell proliferation assay using T1165.85.2.1 cells.

Biochem/physiol Actions

Interleukin-6 (IL-6) is a multifunctional protein originally discovered in the media of cells stimulated with double stranded RNA. IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 and TNF-α in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 induces multiple effects, as indicated by its numerous synonyms: plasmacytoma growth factor (PCT-GF), interferon-β-2 (IFN-β2), monocyte derived human B cell growth factor, B cell stimulating factor (BSF-2), hepatocyte stimulating factor (HSF), Interleukin Hybridoma/Plasmacytoma-1 (IL-HP1). In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 also potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors.

Physical form

Lyophilized from a sterile filtered solution with no additives.

assay≥97% (SDS-PAGE)
biological sourcemouse
colorwhite
formlyophilized powder
Gene Informationmouse ... Il6(16193)
impurities≤1.0EU/mg
mol wt~21.7 kDa
packagingpkg of 5 and 25 µg
potency0.02-0.2 ng/mL EC50
Quality Level200
qualityendotoxin tested
recombinantexpressed in E. coli
storage temp.−20°C
technique(s)cell culture | mammalian: suitable
UniProt accession no.P08505
Pack25UG
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